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KMID : 1100220240230010001
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Dementia and Neurocognitive Disorders
2024 Volume.23 No. 1 p.1 ~ p.10
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Harnessing the Power of Voice: A Deep Neural Network Model for Alzheimer’s Disease Detection
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Park Chan-Young
Kim Min-Soo
Shim Yong-Soo
Ryoo Na-Young
Choi Hyun-Joo
Jeong Ho-Tae
Yun Gi-Hyun
Lee Hun-Boc
Kim Hyung-Ryul
Kim Sang-Yun
Youn Young-Chul
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Abstract
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Background and Purpose: Voice, reflecting cerebral functions, holds potential for analyzing and understanding brain function, especially in the context of cognitive impairment (CI) and Alzheimer’s disease (AD). This study used voice data to distinguish between normal cognition and CI or Alzheimer’s disease dementia (ADD).
Methods: This study enrolled 3 groups of subjects: 1) 52 subjects with subjective cognitive decline; 2) 110 subjects with mild CI; and 3) 59 subjects with ADD. Voice features were extracted using Mel-frequency cepstral coefficients and Chroma.
Results: A deep neural network (DNN) model showed promising performance, with an accuracy of roughly 81% in 10 trials in predicting ADD, which increased to an average value of about 82.0%±1.6% when evaluated against unseen test dataset.
Conclusions: Although results did not demonstrate the level of accuracy necessary for a definitive clinical tool, they provided a compelling proof-of-concept for the potential use of voice data in cognitive status assessment. DNN algorithms using voice offer a promising approach to early detection of AD. They could improve the accuracy and accessibility of diagnosis, ultimately leading to better outcomes for patients.
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KEYWORD
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Voice, Machine Learning, Artificial Intelligence, Alzheimer Disease, Phonetics
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